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Detection of Extended Spectrum β-lactamase Production Among Uropathogens

BACKGROUND: Detection of extended spectrum β-lactamase (ESBL) production among uropathogens is an important marker of endemicity. AIM: Intervention of this endemic transmission is important for the control of initial outbreak of ESBL producing organisms in a hospital or specialized unit of hospital....

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Detalles Bibliográficos
Autores principales: Aggarwal, Ritu, Chaudhary, Uma, Sikka, Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167965/
https://www.ncbi.nlm.nih.gov/pubmed/21938241
http://dx.doi.org/10.4103/0974-2727.44423
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author Aggarwal, Ritu
Chaudhary, Uma
Sikka, Rama
author_facet Aggarwal, Ritu
Chaudhary, Uma
Sikka, Rama
author_sort Aggarwal, Ritu
collection PubMed
description BACKGROUND: Detection of extended spectrum β-lactamase (ESBL) production among uropathogens is an important marker of endemicity. AIM: Intervention of this endemic transmission is important for the control of initial outbreak of ESBL producing organisms in a hospital or specialized unit of hospital. MATERIALS AND METHODS: During the study period of one and a half months, 1,551 urine samples were processed for significant bacteriuria. Two hundred gram negative bacterial isolates were tested for ESBL production. Antimicrobial sensitivity pattern was ascertained for ESBL producing isolates. RESULTS: ESBL production was seen in 36% of isolates. All the isolates were multidrug resistant with uniform sensitivity to imipenem. CONCLUSION: This study reveals the significant prevalence of ESBL producing organisms in this north Indian tertiary care hospital. Constant revision of antibiotic policies with infection control interventions is suggested.
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spelling pubmed-31679652011-09-21 Detection of Extended Spectrum β-lactamase Production Among Uropathogens Aggarwal, Ritu Chaudhary, Uma Sikka, Rama J Lab Physicians Original Article BACKGROUND: Detection of extended spectrum β-lactamase (ESBL) production among uropathogens is an important marker of endemicity. AIM: Intervention of this endemic transmission is important for the control of initial outbreak of ESBL producing organisms in a hospital or specialized unit of hospital. MATERIALS AND METHODS: During the study period of one and a half months, 1,551 urine samples were processed for significant bacteriuria. Two hundred gram negative bacterial isolates were tested for ESBL production. Antimicrobial sensitivity pattern was ascertained for ESBL producing isolates. RESULTS: ESBL production was seen in 36% of isolates. All the isolates were multidrug resistant with uniform sensitivity to imipenem. CONCLUSION: This study reveals the significant prevalence of ESBL producing organisms in this north Indian tertiary care hospital. Constant revision of antibiotic policies with infection control interventions is suggested. Medknow Publications 2009 /pmc/articles/PMC3167965/ /pubmed/21938241 http://dx.doi.org/10.4103/0974-2727.44423 Text en © Journal of Laboratory Physicians http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Aggarwal, Ritu
Chaudhary, Uma
Sikka, Rama
Detection of Extended Spectrum β-lactamase Production Among Uropathogens
title Detection of Extended Spectrum β-lactamase Production Among Uropathogens
title_full Detection of Extended Spectrum β-lactamase Production Among Uropathogens
title_fullStr Detection of Extended Spectrum β-lactamase Production Among Uropathogens
title_full_unstemmed Detection of Extended Spectrum β-lactamase Production Among Uropathogens
title_short Detection of Extended Spectrum β-lactamase Production Among Uropathogens
title_sort detection of extended spectrum β-lactamase production among uropathogens
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167965/
https://www.ncbi.nlm.nih.gov/pubmed/21938241
http://dx.doi.org/10.4103/0974-2727.44423
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