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Acinetobacter Septicemia in Neonates Admitted to Intensive Care Units

BACKGROUND: Acinetobacter species are gaining importance as potential pathogens in neonatal septicemia because of their frequent isolation and multidrug resistance. AIMS AND OBJECTIVES: The aim of the present study was to evaluate the role of Acinetobacter spp. as important pathogens in neonatal blo...

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Autores principales: Shete, Vishal B, Ghadage, Dnyaneshwari P, Muley, Vrishali A, Bhore, Arvind V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167973/
https://www.ncbi.nlm.nih.gov/pubmed/21938255
http://dx.doi.org/10.4103/0974-2727.59704
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author Shete, Vishal B
Ghadage, Dnyaneshwari P
Muley, Vrishali A
Bhore, Arvind V
author_facet Shete, Vishal B
Ghadage, Dnyaneshwari P
Muley, Vrishali A
Bhore, Arvind V
author_sort Shete, Vishal B
collection PubMed
description BACKGROUND: Acinetobacter species are gaining importance as potential pathogens in neonatal septicemia because of their frequent isolation and multidrug resistance. AIMS AND OBJECTIVES: The aim of the present study was to evaluate the role of Acinetobacter spp. as important pathogens in neonatal blood stream infection, to identify the associated risk factors, and to evaluate the drug sensitivity pattern. MATERIALS AND METHODS: Blood samples of infected neonates were studied bacteriologically. Cases of Acinetobacter septicemia were identified. Speciation of Acinetobacter species was done. Various risk factors were identified. The drug-sensitivity test was done. RESULTS: A total of 26 Acinetobacter septicemia cases were identified by blood culture. Acb complex strains predominated. Institutional birth and preterm birth were identified as the most frequent significant risk factors. 11.3% mortality rate was recorded. Acb complex strains exhibited a multi-drug resistant pattern. No carbapenem resistance was observed. CONCLUSION: Acinetobacter should be added to the list of organisms causing severe nosocomial infection in neonatal intensive care units. Continuous bacteriological surveillance, implementation of infection control policies, careful disinfection of intensive care equipment, and rational antibiotic use are required for control of such infections.
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spelling pubmed-31679732011-09-21 Acinetobacter Septicemia in Neonates Admitted to Intensive Care Units Shete, Vishal B Ghadage, Dnyaneshwari P Muley, Vrishali A Bhore, Arvind V J Lab Physicians Original Article BACKGROUND: Acinetobacter species are gaining importance as potential pathogens in neonatal septicemia because of their frequent isolation and multidrug resistance. AIMS AND OBJECTIVES: The aim of the present study was to evaluate the role of Acinetobacter spp. as important pathogens in neonatal blood stream infection, to identify the associated risk factors, and to evaluate the drug sensitivity pattern. MATERIALS AND METHODS: Blood samples of infected neonates were studied bacteriologically. Cases of Acinetobacter septicemia were identified. Speciation of Acinetobacter species was done. Various risk factors were identified. The drug-sensitivity test was done. RESULTS: A total of 26 Acinetobacter septicemia cases were identified by blood culture. Acb complex strains predominated. Institutional birth and preterm birth were identified as the most frequent significant risk factors. 11.3% mortality rate was recorded. Acb complex strains exhibited a multi-drug resistant pattern. No carbapenem resistance was observed. CONCLUSION: Acinetobacter should be added to the list of organisms causing severe nosocomial infection in neonatal intensive care units. Continuous bacteriological surveillance, implementation of infection control policies, careful disinfection of intensive care equipment, and rational antibiotic use are required for control of such infections. Medknow Publications 2009 /pmc/articles/PMC3167973/ /pubmed/21938255 http://dx.doi.org/10.4103/0974-2727.59704 Text en © Journal of Laboratory Physicians http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Shete, Vishal B
Ghadage, Dnyaneshwari P
Muley, Vrishali A
Bhore, Arvind V
Acinetobacter Septicemia in Neonates Admitted to Intensive Care Units
title Acinetobacter Septicemia in Neonates Admitted to Intensive Care Units
title_full Acinetobacter Septicemia in Neonates Admitted to Intensive Care Units
title_fullStr Acinetobacter Septicemia in Neonates Admitted to Intensive Care Units
title_full_unstemmed Acinetobacter Septicemia in Neonates Admitted to Intensive Care Units
title_short Acinetobacter Septicemia in Neonates Admitted to Intensive Care Units
title_sort acinetobacter septicemia in neonates admitted to intensive care units
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167973/
https://www.ncbi.nlm.nih.gov/pubmed/21938255
http://dx.doi.org/10.4103/0974-2727.59704
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