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2′‐5′ oligoadenylate synthetase 1 polymorphism is associated with prostate cancer

BACKGROUND: The antiviral, proapoptotic, antiproliferative gene 2′‐5′ oligoadenylate synthetase (2‐5OAS1) converts adenosine triphosphate into a series of 2′‐5′ oligoadenylates (2‐5A). In turn, 2‐5A activates latent ribonuclease (RNaseL), a candidate hereditary prostate cancer gene. OAS1 polymorphis...

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Detalles Bibliográficos
Autores principales:	Mandal, Sanjay, Abebe, Fisseha, Chaudhary, Jaideep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167978/ https://www.ncbi.nlm.nih.gov/pubmed/21638280 http://dx.doi.org/10.1002/cncr.26219

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