Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis

We present 2 cases of Niemann Pick disease, type B with secondary sea-blue histiocytosis. Strikingly, in both cases the Pick cells were positive for tartrate resistant acid phosphatase, a finding hitherto described only in Gaucher cells. This report highlights the importance of this finding as a pot...

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Detalles Bibliográficos
Autores principales: Sharma, P., Kar, R., Dutta, S., Pati, H.P., Saxena, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2009
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168231/
https://www.ncbi.nlm.nih.gov/pubmed/30256875
http://dx.doi.org/10.4081/ejh.2009.e22
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author Sharma, P.
Kar, R.
Dutta, S.
Pati, H.P.
Saxena, R.
author_facet Sharma, P.
Kar, R.
Dutta, S.
Pati, H.P.
Saxena, R.
author_sort Sharma, P.
collection PubMed
description We present 2 cases of Niemann Pick disease, type B with secondary sea-blue histiocytosis. Strikingly, in both cases the Pick cells were positive for tartrate resistant acid phosphatase, a finding hitherto described only in Gaucher cells. This report highlights the importance of this finding as a potential cytochemical diagnostic pitfall in the diagnosis of Niemann Pick disease.
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spelling pubmed-31682312011-11-09 Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis Sharma, P. Kar, R. Dutta, S. Pati, H.P. Saxena, R. Eur J Histochem Original Paper We present 2 cases of Niemann Pick disease, type B with secondary sea-blue histiocytosis. Strikingly, in both cases the Pick cells were positive for tartrate resistant acid phosphatase, a finding hitherto described only in Gaucher cells. This report highlights the importance of this finding as a potential cytochemical diagnostic pitfall in the diagnosis of Niemann Pick disease. PAGEPress Publications 2009-09-30 /pmc/articles/PMC3168231/ /pubmed/30256875 http://dx.doi.org/10.4081/ejh.2009.e22 Text en ©2009 European Journal of Histochemistry
spellingShingle Original Paper
Sharma, P.
Kar, R.
Dutta, S.
Pati, H.P.
Saxena, R.
Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis
title Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis
title_full Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis
title_fullStr Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis
title_full_unstemmed Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis
title_short Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis
title_sort niemann-pick disease, type b with trap-positive storage cells and secondary sea blue histiocytosis
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168231/
https://www.ncbi.nlm.nih.gov/pubmed/30256875
http://dx.doi.org/10.4081/ejh.2009.e22
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