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Activation of PKC-ε counteracts maturation and apoptosis of HL-60 myeloid leukemic cells in response to TNF family members

Protein kinase C (PKC)-ε, a component of the serine/threo-nine PKC family, has been shown to influence the survival and differentiation pathways of normal hematopoietic cells. Here, we have modulated the activity of PKC-ε with specific small molecule activator or inhibitor peptides. PKC-ε inhibitor...

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Detalles Bibliográficos
Autores principales: Gonelli, A., Milani, D., Rimondi, E., Voltan, R., Grill, V., Celeghini, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168235/
https://www.ncbi.nlm.nih.gov/pubmed/30256868
http://dx.doi.org/10.4081/ejh.2009.e21