Cargando…
Molecular Basis of Ligand Dissociation in β-Adrenergic Receptors
The important and diverse biological functions of β-adrenergic receptors (βARs) have promoted the search for compounds to stimulate or inhibit their activity. In this regard, unraveling the molecular basis of ligand binding/unbinding events is essential to understand the pharmacological properties o...
Autores principales: | González, Angel, Perez-Acle, Tomas, Pardo, Leonardo, Deupi, Xavier |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168429/ https://www.ncbi.nlm.nih.gov/pubmed/21915263 http://dx.doi.org/10.1371/journal.pone.0023815 |
Ejemplares similares
-
Internalization Dissociates β(2)-Adrenergic Receptors
por: Lan, Tien-Hung, et al.
Publicado: (2011) -
Agonist binding by the β(2)-adrenergic receptor: an effect of receptor conformation on ligand association–dissociation characteristics
por: Plazinska, Anita, et al.
Publicado: (2015) -
Ligand-regulated oligomerization of β(2)-adrenoceptors in a model lipid bilayer
por: Fung, Juan José, et al.
Publicado: (2009) -
Mutual Enhancement of Opioid and Adrenergic Receptors by Combinations of Opioids and Adrenergic Ligands Is Reflected in Molecular Complementarity of Ligands: Drug Development Possibilities
por: Root-Bernstein, Robert, et al.
Publicado: (2019) -
Allosteric Effect of Nanobody Binding on Ligand-Specific
Active States of the β2 Adrenergic Receptor
por: Chen, Yue, et al.
Publicado: (2021)