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Statistical Methods in Recent HIV Noninferiority Trials: Reanalysis of 11 Trials

BACKGROUND: In recent years the “noninferiority” trial has emerged as the new standard design for HIV drug development among antiretroviral patients often with a primary endpoint based on the difference in success rates between the two treatment groups. Different statistical methods have been introd...

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Detalles Bibliográficos
Autor principal: Flandre, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168436/
https://www.ncbi.nlm.nih.gov/pubmed/21915255
http://dx.doi.org/10.1371/journal.pone.0022871