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Overexpression of Chitinase 3-Like 1/YKL-40 in Lung-Specific IL-18-Transgenic Mice, Smokers and COPD

We analyzed the lung mRNA expression profiles of a murine model of COPD developed using a lung-specific IL-18-transgenic mouse. In this transgenic mouse, the expression of 608 genes was found to vary more than 2-fold in comparison with control WT mice, and was clustered into 4 groups. The expression...

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Detalles Bibliográficos
Autores principales:	Sakazaki, Yuki, Hoshino, Tomoaki, Takei, Satoko, Sawada, Masanori, Oda, Hanako, Takenaka, Shin-ichi, Imaoka, Haruki, Matsunaga, Kazuko, Ota, Toshio, Abe, Yuzuru, Miki, Ichiro, Fujimoto, Kiminori, Kawayama, Tomotaka, Kato, Seiya, Aizawa, Hisamichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168485/ https://www.ncbi.nlm.nih.gov/pubmed/21915293 http://dx.doi.org/10.1371/journal.pone.0024177

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