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Insights into the Role of Yeast eIF2A in IRES-Mediated Translation

Eukaryotic initiation factor 2A is a single polypeptide that acts to negatively regulate IRES-mediated translation during normal cellular conditions. We have found that eIF2A (encoded by YGR054w) abundance is reduced at both the mRNA and protein level during 6% ethanol stress (or 37°C heat shock) un...

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Detalles Bibliográficos
Autores principales: Reineke, Lucas C., Cao, Yu, Baus, Diane, Hossain, Nasheed M., Merrick, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168509/
https://www.ncbi.nlm.nih.gov/pubmed/21915340
http://dx.doi.org/10.1371/journal.pone.0024492

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