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Analysis of osteoarthritis in a mouse model of the progeroid human DNA repair syndrome trichothiodystrophy
The increasing average age in developed societies is paralleled by an increase in the prevalence of many age-related diseases such as osteoarthritis (OA), which is characterized by deformation of the joint due to cartilage damage and increased turnover of subchondral bone. Consequently, deficiency i...
Autores principales: | Botter, Sander M., Zar, Michel, van Osch, Gerjo J. V. M, van Steeg, Harry, Dollé, Martijn E. T., Hoeijmakers, Jan H. J., Weinans, Harrie, van Leeuwen, Johannes P. T. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168596/ https://www.ncbi.nlm.nih.gov/pubmed/20820927 http://dx.doi.org/10.1007/s11357-010-9175-3 |
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