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Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity
Increased susceptibility to infections, particularly respiratory viral infections, is a hallmark of advancing age. The underlying mechanisms are not well understood, and there is a scarcity of information regarding the contribution of the innate immune system, which is the first line of defense agai...
Autores principales: | Sridharan, Aishwarya, Esposo, Marc, Kaushal, Khushboo, Tay, Jia, Osann, Kathyrn, Agrawal, Sudhanshu, Gupta, Sudhir, Agrawal, Anshu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168606/ https://www.ncbi.nlm.nih.gov/pubmed/20953722 http://dx.doi.org/10.1007/s11357-010-9191-3 |
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