Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

DNA recombination pathways are cell cycle regulated to coordinate with replication. Cyclin-dependent kinase (Cdk1) promotes efficient 5'-strand resection at DNA double strand breaks (DSBs), the initial step of homologous recombination and damage checkpoint activation. The Mre11–Rad50–Xrs2 compl...

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Detalles Bibliográficos
Autores principales: Chen, Xuefeng, Niu, Hengyao, Chung, Woo-Hyun, Zhu, Zhu, Papusha, Alma, Shim, Eun Yong, Lee, Sang Eun, Sung, Patrick, Ira, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168961/
https://www.ncbi.nlm.nih.gov/pubmed/21841787
http://dx.doi.org/10.1038/nsmb.2105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168961/
https://www.ncbi.nlm.nih.gov/pubmed/21841787
http://dx.doi.org/10.1038/nsmb.2105

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