The structural basis of RNA-catalyzed RNA polymerization

Early life presumably required polymerase ribozymes capable of replicating RNA. Known polymerase ribozymes best approximating such replicases use as their catalytic engine an RNA-ligase ribozyme originally selected from random RNA sequences. Here, we report 3.15 Å crystal structures of this ligase t...

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Detalles Bibliográficos
Autores principales: Shechner, David M., Bartel, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169305/
https://www.ncbi.nlm.nih.gov/pubmed/21857665
http://dx.doi.org/10.1038/nsmb.2107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169305/
https://www.ncbi.nlm.nih.gov/pubmed/21857665
http://dx.doi.org/10.1038/nsmb.2107

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