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Structure of RiVax: a recombinant ricin vaccine
RiVax is a recombinant protein that is currently under clinical development as part of a human vaccine to protect against ricin poisoning. RiVax includes ricin A-chain (RTA) residues 1–267 with two intentional amino-acid substitutions, V76M and Y80A, aimed at reducing toxicity. Here, the crystal str...
Autores principales: | Legler, Patricia M., Brey, Robert N., Smallshaw, Joan E., Vitetta, Ellen S., Millard, Charles B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169317/ https://www.ncbi.nlm.nih.gov/pubmed/21904036 http://dx.doi.org/10.1107/S0907444911026771 |
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