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Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2

BACKGROUND: The HIV-1 accessory protein Nef is an important determinant of lentiviral pathogenicity that contributes to disease progression by enhancing viral replication and other poorly understood mechanisms. Nef mediates diverse functions including downmodulation of cell surface CD4 and MHC Class...

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Detalles Bibliográficos
Autores principales:	Olivieri, Kevin C, Mukerji, Joya, Gabuzda, Dana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169461/ https://www.ncbi.nlm.nih.gov/pubmed/21819585 http://dx.doi.org/10.1186/1742-4690-8-64

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