Cargando…
A previously functional tetracycline-regulated transactivator fails to target gene expression to the bone
BACKGROUND: The tetracycline-controlled transactivator system is a powerful tool to control gene expression in vitro and to generate consistent and conditional transgenic in vivo model organisms. It has been widely used to study gene function and to explore pathological mechanisms involved in human...
Autores principales: | Schmidt, Eva, Eriksson, Maria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169473/ https://www.ncbi.nlm.nih.gov/pubmed/21835026 http://dx.doi.org/10.1186/1756-0500-4-282 |
Ejemplares similares
-
Low Levels of the Reverse Transactivator Fail to Induce Target Transgene Expression in Vascular Smooth Muscle Cells
por: Viceconte, Nikenza, et al.
Publicado: (2014) -
Improvement of the reverse tetracycline transactivator by single amino acid substitutions that reduce leaky target gene expression to undetectable levels
por: Roney, Ian J., et al.
Publicado: (2016) -
Variability of Inducible Expression across the Hematopoietic System of Tetracycline Transactivator Transgenic Mice
por: Takiguchi, Megumi, et al.
Publicado: (2013) -
A Tetracycline-Repressible Transactivator System to Study Essential Genes in Malaria Parasites
por: Pino, Paco, et al.
Publicado: (2012) -
Brain-wide distribution of reporter expression in five transgenic tetracycline-transactivator mouse lines
por: Lillehaug, Sveinung, et al.
Publicado: (2019)