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A codon substitution model that incorporates the effect of the GC contents, the gene density and the density of CpG islands of human chromosomes
BACKGROUND: Developing a model for codon substitutions is essential for the analyses of protein sequences. Recent studies on the mutation rates in the non-coding regions have shown that CpG mutation rates in the human genome are negatively correlated to the local GC content and to the densities of f...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169530/ https://www.ncbi.nlm.nih.gov/pubmed/21819607 http://dx.doi.org/10.1186/1471-2164-12-397 |