Rationally Designed Interfacial Peptides Are Efficient In Vitro Inhibitors of HIV-1 Capsid Assembly with Antiviral Activity

Virus capsid assembly constitutes an attractive target for the development of antiviral therapies; a few experimental inhibitors of this process for HIV-1 and other viruses have been identified by screening compounds or by selection from chemical libraries. As a different, novel approach we have und...

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Detalles Bibliográficos
Autores principales: Bocanegra, Rebeca, Nevot, María, Doménech, Rosa, López, Inmaculada, Abián, Olga, Rodríguez-Huete, Alicia, Cavasotto, Claudio N., Velázquez-Campoy, Adrián, Gómez, Javier, Martínez, Miguel Ángel, Neira, José Luis, Mateu, Mauricio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169566/
https://www.ncbi.nlm.nih.gov/pubmed/21931621
http://dx.doi.org/10.1371/journal.pone.0023877

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