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Cyclic AMP Control Measured in Two Compartments in HEK293 Cells: Phosphodiesterase K(M) Is More Important than Phosphodiesterase Localization
The intracellular second messenger cyclic AMP (cAMP) is degraded by phosphodiesterases (PDE). The knowledge of individual families and subtypes of PDEs is considerable, but how the different PDEs collaborate in the cell to control a cAMP signal is still not fully understood. In order to investigate...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169605/ https://www.ncbi.nlm.nih.gov/pubmed/21931705 http://dx.doi.org/10.1371/journal.pone.0024392 |