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DAF-16 and Δ(9) Desaturase Genes Promote Cold Tolerance in Long-Lived Caenorhabditis elegans age-1 Mutants

In Caenorhabditis elegans, mutants of the conserved insulin/IGF-1 signalling (IIS) pathway are long-lived and stress resistant due to the altered expression of DAF-16 target genes such as those involved in cellular defence and metabolism. The three Δ(9) desaturase genes, fat-5, fat-6 and fat-7, are...

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Detalles Bibliográficos
Autores principales:	Savory, Fiona R., Sait, Steven M., Hope, Ian A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169625/ https://www.ncbi.nlm.nih.gov/pubmed/21931751 http://dx.doi.org/10.1371/journal.pone.0024550

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