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COSEHC global vascular risk management quality improvement program: rationale and design
BACKGROUND: The Consortium for Southeastern Hypertension Control (COSEHC) promotes global risk factor management in patients with metabolic syndrome. The COSEHC Global Vascular Risk Management Study (GVRM) intends to quantify these efforts on long-term patient outcomes. The objectives of this study...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169675/ https://www.ncbi.nlm.nih.gov/pubmed/21931496 http://dx.doi.org/10.2147/VHRM.S13746 |
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author | Ferrario, Carlos M Moore, Michael A Bestermann, William Colby, Chris Exuzides, Alex Simmons, Debra Panjabi, Sumeet |
author_facet | Ferrario, Carlos M Moore, Michael A Bestermann, William Colby, Chris Exuzides, Alex Simmons, Debra Panjabi, Sumeet |
author_sort | Ferrario, Carlos M |
collection | PubMed |
description | BACKGROUND: The Consortium for Southeastern Hypertension Control (COSEHC) promotes global risk factor management in patients with metabolic syndrome. The COSEHC Global Vascular Risk Management Study (GVRM) intends to quantify these efforts on long-term patient outcomes. The objectives of this study were to present baseline demographics of patients enrolled in the GVRM, calculate a modified COSEHC risk score using 11 variables (COSEHC-11), and compare it with the original COSEHC-17 and Framingham, Prospective Cardiovascular Münster (PROCAM), and Systemic Coronary Risk Evaluation (SCORE) risk scores. METHODS: Deidentified electronic medical records of enrolled patients were used to calculate the risk scores. The ability of the COSEHC-11 score to predict the COSEHC-17 score was assessed by regression analysis. Raw risk scores were converted to probability estimates of fatal coronary heart disease (CHD) and compared with predicted risks from other algorithms. RESULTS: Of the 177,404 patients enrolled, 43,676 had data for all 11 variables. The COSEHC-11 score (mean ± standard deviation) of these 43,676 patients was 31.75 ± 11.66, implying a five-year fatal CHD risk of 1.4%. The COSEHC-11 score was highly predictive of the COSEHC-17 score (R(2) = 0.93; P < 0.0001) and correlated well with the SCORE algorithm. CONCLUSION: The COSEHC-11 risk score is statistically similar to the COSEHC-17 risk score and should be a viable tool for evaluating its ability to predict five-year cardiovascular mortality in the coming years. |
format | Online Article Text |
id | pubmed-3169675 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-31696752011-09-19 COSEHC global vascular risk management quality improvement program: rationale and design Ferrario, Carlos M Moore, Michael A Bestermann, William Colby, Chris Exuzides, Alex Simmons, Debra Panjabi, Sumeet Vasc Health Risk Manag Original Research BACKGROUND: The Consortium for Southeastern Hypertension Control (COSEHC) promotes global risk factor management in patients with metabolic syndrome. The COSEHC Global Vascular Risk Management Study (GVRM) intends to quantify these efforts on long-term patient outcomes. The objectives of this study were to present baseline demographics of patients enrolled in the GVRM, calculate a modified COSEHC risk score using 11 variables (COSEHC-11), and compare it with the original COSEHC-17 and Framingham, Prospective Cardiovascular Münster (PROCAM), and Systemic Coronary Risk Evaluation (SCORE) risk scores. METHODS: Deidentified electronic medical records of enrolled patients were used to calculate the risk scores. The ability of the COSEHC-11 score to predict the COSEHC-17 score was assessed by regression analysis. Raw risk scores were converted to probability estimates of fatal coronary heart disease (CHD) and compared with predicted risks from other algorithms. RESULTS: Of the 177,404 patients enrolled, 43,676 had data for all 11 variables. The COSEHC-11 score (mean ± standard deviation) of these 43,676 patients was 31.75 ± 11.66, implying a five-year fatal CHD risk of 1.4%. The COSEHC-11 score was highly predictive of the COSEHC-17 score (R(2) = 0.93; P < 0.0001) and correlated well with the SCORE algorithm. CONCLUSION: The COSEHC-11 risk score is statistically similar to the COSEHC-17 risk score and should be a viable tool for evaluating its ability to predict five-year cardiovascular mortality in the coming years. Dove Medical Press 2010 2010-12-13 /pmc/articles/PMC3169675/ /pubmed/21931496 http://dx.doi.org/10.2147/VHRM.S13746 Text en © 2010 Ferrario et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Original Research Ferrario, Carlos M Moore, Michael A Bestermann, William Colby, Chris Exuzides, Alex Simmons, Debra Panjabi, Sumeet COSEHC global vascular risk management quality improvement program: rationale and design |
title | COSEHC global vascular risk management quality improvement program: rationale and design |
title_full | COSEHC global vascular risk management quality improvement program: rationale and design |
title_fullStr | COSEHC global vascular risk management quality improvement program: rationale and design |
title_full_unstemmed | COSEHC global vascular risk management quality improvement program: rationale and design |
title_short | COSEHC global vascular risk management quality improvement program: rationale and design |
title_sort | cosehc global vascular risk management quality improvement program: rationale and design |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169675/ https://www.ncbi.nlm.nih.gov/pubmed/21931496 http://dx.doi.org/10.2147/VHRM.S13746 |
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