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Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study

Hexane, ethyl acetate, ethanol and methanol extracts of Psidium guajava, Terminalia chebula, Mimusops elengi and Achyranthes aspera were tested against the dental caries causing bacteria Streptococcus mutans and fungus Candida albicans isolated from caries infected patients. All the four extracts of...

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Autores principales: Jebashree, H. Shyla, Kingsley, S. Jayasurya, Sathish, Emmanuel S., Devapriya, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169913/
https://www.ncbi.nlm.nih.gov/pubmed/21991479
http://dx.doi.org/10.5402/2011/541421
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author Jebashree, H. Shyla
Kingsley, S. Jayasurya
Sathish, Emmanuel S.
Devapriya, D.
author_facet Jebashree, H. Shyla
Kingsley, S. Jayasurya
Sathish, Emmanuel S.
Devapriya, D.
author_sort Jebashree, H. Shyla
collection PubMed
description Hexane, ethyl acetate, ethanol and methanol extracts of Psidium guajava, Terminalia chebula, Mimusops elengi and Achyranthes aspera were tested against the dental caries causing bacteria Streptococcus mutans and fungus Candida albicans isolated from caries infected patients. All the four extracts of P. guajava showed activity against both S. mutans and C. albicans. Maximum zone of inhibition was observed in ethyl acetate of P. guajava. The four extracts of T. chebula and M. elengi showed antibacterial activity against S. mutans. M. elengi extracts and ethanol extract of T. chebula did not show any antifungal activity against C. albicans. Except for the hexane extract of A. aspera, the other three extracts showed activity against the tested microbes. The ethyl acetate P. guajava leaf extract showed the minimum inhibitory concentration (MIC) against S. mutans to be <0.076 mg/mL in both MHB and BHI. The P. guajava ethyl acetate extract was subjected to GC-MS.
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spelling pubmed-31699132011-10-11 Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study Jebashree, H. Shyla Kingsley, S. Jayasurya Sathish, Emmanuel S. Devapriya, D. ISRN Dent Research Article Hexane, ethyl acetate, ethanol and methanol extracts of Psidium guajava, Terminalia chebula, Mimusops elengi and Achyranthes aspera were tested against the dental caries causing bacteria Streptococcus mutans and fungus Candida albicans isolated from caries infected patients. All the four extracts of P. guajava showed activity against both S. mutans and C. albicans. Maximum zone of inhibition was observed in ethyl acetate of P. guajava. The four extracts of T. chebula and M. elengi showed antibacterial activity against S. mutans. M. elengi extracts and ethanol extract of T. chebula did not show any antifungal activity against C. albicans. Except for the hexane extract of A. aspera, the other three extracts showed activity against the tested microbes. The ethyl acetate P. guajava leaf extract showed the minimum inhibitory concentration (MIC) against S. mutans to be <0.076 mg/mL in both MHB and BHI. The P. guajava ethyl acetate extract was subjected to GC-MS. International Scholarly Research Network 2011 2011-06-08 /pmc/articles/PMC3169913/ /pubmed/21991479 http://dx.doi.org/10.5402/2011/541421 Text en Copyright © 2011 H. Shyla Jebashree et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Jebashree, H. Shyla
Kingsley, S. Jayasurya
Sathish, Emmanuel S.
Devapriya, D.
Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study
title Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study
title_full Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study
title_fullStr Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study
title_full_unstemmed Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study
title_short Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study
title_sort antimicrobial activity of few medicinal plants against clinically isolated human cariogenic pathogens—an in vitro study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169913/
https://www.ncbi.nlm.nih.gov/pubmed/21991479
http://dx.doi.org/10.5402/2011/541421
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