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Logical network of genotoxic stress-induced NF-κB signal transduction predicts putative target structures for therapeutic intervention strategies

Genotoxic stress is induced by a broad range of DNA-damaging agents and could lead to a variety of human diseases including cancer. DNA damage is also therapeutically induced for cancer treatment with the aim to eliminate tumor cells. However, the effectiveness of radio- and chemotherapy is strongly...

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Detalles Bibliográficos
Autores principales:	Poltz, Rainer, Franke, Raimo, Schweitzer, Katrin, Klamt, Steffen, Gilles, Ernst-Dieter, Naumann, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2009
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169943/ https://www.ncbi.nlm.nih.gov/pubmed/21918620

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