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Smoking cessation: an economic analysis and review of varenicline
Despite efforts to decrease tobacco use, smoking continues to be a leading cause of preventable morbidity and premature death. The associated economic burden is substantial, both in the form of direct costs (healthcare expenditures) and indirect costs (lost productivity), regardless of whether the b...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169991/ https://www.ncbi.nlm.nih.gov/pubmed/21935304 |
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author | Faulkner, Michele A |
author_facet | Faulkner, Michele A |
author_sort | Faulkner, Michele A |
collection | PubMed |
description | Despite efforts to decrease tobacco use, smoking continues to be a leading cause of preventable morbidity and premature death. The associated economic burden is substantial, both in the form of direct costs (healthcare expenditures) and indirect costs (lost productivity), regardless of whether the burden is assessed from the standpoint of an employer, a health plan, or society as a whole. Cessation programs are considered among the most cost-effective in healthcare, and are often used as a benchmark for other medical interventions. This analysis specifically considers the cost-effectiveness of varenicline, a novel α(4)β(2) partial agonist used for smoking cessation, in comparison to other approved therapies. Clinical trial data have demonstrated that varenicline has the ability to decrease cravings and withdrawal symptoms, and lessen positive reinforcement associated with smoking. Varenicline’s novel mechanism has translated into superior efficacy in comparison to other available therapies. For this reason, despite an initial cost that typically exceeds that of other medications, varenicline is a cost-effective option for smoking cessation. |
format | Online Article Text |
id | pubmed-3169991 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-31699912011-09-20 Smoking cessation: an economic analysis and review of varenicline Faulkner, Michele A Clinicoecon Outcomes Res Review Despite efforts to decrease tobacco use, smoking continues to be a leading cause of preventable morbidity and premature death. The associated economic burden is substantial, both in the form of direct costs (healthcare expenditures) and indirect costs (lost productivity), regardless of whether the burden is assessed from the standpoint of an employer, a health plan, or society as a whole. Cessation programs are considered among the most cost-effective in healthcare, and are often used as a benchmark for other medical interventions. This analysis specifically considers the cost-effectiveness of varenicline, a novel α(4)β(2) partial agonist used for smoking cessation, in comparison to other approved therapies. Clinical trial data have demonstrated that varenicline has the ability to decrease cravings and withdrawal symptoms, and lessen positive reinforcement associated with smoking. Varenicline’s novel mechanism has translated into superior efficacy in comparison to other available therapies. For this reason, despite an initial cost that typically exceeds that of other medications, varenicline is a cost-effective option for smoking cessation. Dove Medical Press 2009-06-24 /pmc/articles/PMC3169991/ /pubmed/21935304 Text en © 2009 Faulkner, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Review Faulkner, Michele A Smoking cessation: an economic analysis and review of varenicline |
title | Smoking cessation: an economic analysis and review of varenicline |
title_full | Smoking cessation: an economic analysis and review of varenicline |
title_fullStr | Smoking cessation: an economic analysis and review of varenicline |
title_full_unstemmed | Smoking cessation: an economic analysis and review of varenicline |
title_short | Smoking cessation: an economic analysis and review of varenicline |
title_sort | smoking cessation: an economic analysis and review of varenicline |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169991/ https://www.ncbi.nlm.nih.gov/pubmed/21935304 |
work_keys_str_mv | AT faulknermichelea smokingcessationaneconomicanalysisandreviewofvarenicline |