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Integrative Cancer Genomics (IntOGen) in Biomart

Recently, we created IntOGen, a resource to integrate a large amount of cancer genomic data. IntOGen aims at facilitating the detection of the most recurrent alterations that drive tumorigenesis. It collates, annotates and analyzes high-throughput data about transcriptional, genomic and mutational c...

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Detalles Bibliográficos
Autores principales: Perez-Llamas, Christian, Gundem, Gunes, Lopez-Bigas, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169995/
https://www.ncbi.nlm.nih.gov/pubmed/21903633
http://dx.doi.org/10.1093/database/bar039
Descripción
Sumario:Recently, we created IntOGen, a resource to integrate a large amount of cancer genomic data. IntOGen aims at facilitating the detection of the most recurrent alterations that drive tumorigenesis. It collates, annotates and analyzes high-throughput data about transcriptional, genomic and mutational changes taking place in tumors from different studies annotated with specific cancer types. Currently, it contains 118 studies for mRNA expression profiling and 188 studies for genomic alterations covering in total 64 different tumor topographies. In this article, we describe the Biomart portal for IntOGen. The portal provides easy access to different types of data and facilitates the bulk download of all the analysis results. Here, we describe the general features of IntOGen and give example queries to demonstrate its use. Database URL: www.intogen.org.