Efficient algorithms for multidimensional global optimization in genetic mapping of complex traits

We present a two-phase strategy for optimizing a multidimensional, nonconvex function arising during genetic mapping of quantitative traits. Such traits are believed to be affected by multiple so called quantitative trait loci (QTL), and searching for d QTL results in a d-dimensional optimization pr...

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Detalles Bibliográficos
Autores principales: Ljungberg, Kajsa, Mishchenko, Kateryna, Holmgren, Sverker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170002/
https://www.ncbi.nlm.nih.gov/pubmed/21918629
http://dx.doi.org/10.2147/AABC.S9240

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