Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra

An 8-year-old patient with genetically confirmed chronic infantile neurological cutaneous and articular syndrome was treated with interleukin-1 receptor antagonist, anakinra. She initially presented with recurrent episodes of fever, rash, chronic fatigue, frequent headaches, ocular involvement (corn...

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Autores principales: Terrada, Celine, Neven, Benedicte, Boddaert, Nathalie, Souied, Eric H, Prieur, Anne Marie, Quartier, Pierre, Lehoang, Phuc, Bodaghi, Bahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170123/
https://www.ncbi.nlm.nih.gov/pubmed/21484180
http://dx.doi.org/10.1007/s12348-010-0018-2
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author Terrada, Celine
Neven, Benedicte
Boddaert, Nathalie
Souied, Eric H
Prieur, Anne Marie
Quartier, Pierre
Lehoang, Phuc
Bodaghi, Bahram
author_facet Terrada, Celine
Neven, Benedicte
Boddaert, Nathalie
Souied, Eric H
Prieur, Anne Marie
Quartier, Pierre
Lehoang, Phuc
Bodaghi, Bahram
author_sort Terrada, Celine
collection PubMed
description An 8-year-old patient with genetically confirmed chronic infantile neurological cutaneous and articular syndrome was treated with interleukin-1 receptor antagonist, anakinra. She initially presented with recurrent episodes of fever, rash, chronic fatigue, frequent headaches, ocular involvement (corneal infiltrate and papillary edema), and permanent increased biologic inflammatory markers. Following treatment with anakinra, all symptoms and inflammation resolved. Ophthalmologic signs normalized. This ophthalmologic description (optic nerve and cornea) has never been illustrated, even if ocular affections are classic in the cryopyrin-associated periodic syndromes.
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spelling pubmed-31701232011-09-26 Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra Terrada, Celine Neven, Benedicte Boddaert, Nathalie Souied, Eric H Prieur, Anne Marie Quartier, Pierre Lehoang, Phuc Bodaghi, Bahram J Ophthalmic Inflamm Infect Brief Report An 8-year-old patient with genetically confirmed chronic infantile neurological cutaneous and articular syndrome was treated with interleukin-1 receptor antagonist, anakinra. She initially presented with recurrent episodes of fever, rash, chronic fatigue, frequent headaches, ocular involvement (corneal infiltrate and papillary edema), and permanent increased biologic inflammatory markers. Following treatment with anakinra, all symptoms and inflammation resolved. Ophthalmologic signs normalized. This ophthalmologic description (optic nerve and cornea) has never been illustrated, even if ocular affections are classic in the cryopyrin-associated periodic syndromes. Springer-Verlag 2011-04-09 /pmc/articles/PMC3170123/ /pubmed/21484180 http://dx.doi.org/10.1007/s12348-010-0018-2 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Brief Report
Terrada, Celine
Neven, Benedicte
Boddaert, Nathalie
Souied, Eric H
Prieur, Anne Marie
Quartier, Pierre
Lehoang, Phuc
Bodaghi, Bahram
Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra
title Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra
title_full Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra
title_fullStr Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra
title_full_unstemmed Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra
title_short Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra
title_sort ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170123/
https://www.ncbi.nlm.nih.gov/pubmed/21484180
http://dx.doi.org/10.1007/s12348-010-0018-2
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