Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls

It has been established that a cationic gold(I)/(R)-DTBM-Segphos or (R)-BINAP complex catalyzes the atropselective intramolecular hydroarylation of alkynes leading to enantioenriched axially chiral 4-aryl-2-quinolinones and 4-arylcoumarins with up to 61% ee.

Detalles Bibliográficos
Autores principales: Shibuya, Tetsuro, Nakamura, Kyosuke, Tanaka, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170204/
https://www.ncbi.nlm.nih.gov/pubmed/21915192
http://dx.doi.org/10.3762/bjoc.7.105
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author Shibuya, Tetsuro
Nakamura, Kyosuke
Tanaka, Ken
author_facet Shibuya, Tetsuro
Nakamura, Kyosuke
Tanaka, Ken
author_sort Shibuya, Tetsuro
collection PubMed
description It has been established that a cationic gold(I)/(R)-DTBM-Segphos or (R)-BINAP complex catalyzes the atropselective intramolecular hydroarylation of alkynes leading to enantioenriched axially chiral 4-aryl-2-quinolinones and 4-arylcoumarins with up to 61% ee.
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spelling pubmed-31702042011-09-13 Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls Shibuya, Tetsuro Nakamura, Kyosuke Tanaka, Ken Beilstein J Org Chem Full Research Paper It has been established that a cationic gold(I)/(R)-DTBM-Segphos or (R)-BINAP complex catalyzes the atropselective intramolecular hydroarylation of alkynes leading to enantioenriched axially chiral 4-aryl-2-quinolinones and 4-arylcoumarins with up to 61% ee. Beilstein-Institut 2011-07-06 /pmc/articles/PMC3170204/ /pubmed/21915192 http://dx.doi.org/10.3762/bjoc.7.105 Text en Copyright © 2011, Shibuya et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Shibuya, Tetsuro
Nakamura, Kyosuke
Tanaka, Ken
Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls
title Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls
title_full Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls
title_fullStr Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls
title_full_unstemmed Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls
title_short Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls
title_sort cationic gold(i) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170204/
https://www.ncbi.nlm.nih.gov/pubmed/21915192
http://dx.doi.org/10.3762/bjoc.7.105
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AT nakamurakyosuke cationicgoldiaxiallychiralbiarylbisphosphinecomplexcatalyzedatropselectivesynthesisofheterobiaryls
AT tanakaken cationicgoldiaxiallychiralbiarylbisphosphinecomplexcatalyzedatropselectivesynthesisofheterobiaryls

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