TP53 and MDM2 gene polymorphisms and risk of hepatocellular carcinoma among Italian patients

BACKGROUND: Single-nucleotide polymorphisms within TP53 gene (codon 72 exon 4, rs1042522, encoding either arginine or proline) and MDM2 promoter (SNP309; rs2279744), have been independently associated with increased risk of several cancer types. Few studies have analysed the role of these polymorphi...

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Detalles Bibliográficos
Autores principales: Di Vuolo, Valeria, Buonaguro, Luigi, Izzo, Francesco, Losito, Simona, Botti, Gerardo, Buonaguro, Franco M, Tornesello, Maria Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170208/
https://www.ncbi.nlm.nih.gov/pubmed/21843334
http://dx.doi.org/10.1186/1750-9378-6-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170208/
https://www.ncbi.nlm.nih.gov/pubmed/21843334
http://dx.doi.org/10.1186/1750-9378-6-13

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