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TP53 and MDM2 gene polymorphisms and risk of hepatocellular carcinoma among Italian patients
BACKGROUND: Single-nucleotide polymorphisms within TP53 gene (codon 72 exon 4, rs1042522, encoding either arginine or proline) and MDM2 promoter (SNP309; rs2279744), have been independently associated with increased risk of several cancer types. Few studies have analysed the role of these polymorphi...
Autores principales: | Di Vuolo, Valeria, Buonaguro, Luigi, Izzo, Francesco, Losito, Simona, Botti, Gerardo, Buonaguro, Franco M, Tornesello, Maria Lina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170208/ https://www.ncbi.nlm.nih.gov/pubmed/21843334 http://dx.doi.org/10.1186/1750-9378-6-13 |
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