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Sustained productivity in recombinant Chinese Hamster Ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype

BACKGROUND: The ability of mammalian cell lines to sustain cell specific productivity (Qp) over the full duration of bioprocess culture is a highly desirable phenotype, but the molecular basis for sustainable productivity has not been previously investigated in detail. In order to identify proteins...

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Detalles Bibliográficos
Autores principales:	Meleady, Paula, Doolan, Padraig, Henry, Michael, Barron, Niall, Keenan, Joanne, O'Sullivan, Finbar, Clarke, Colin, Gammell, Patrick, Melville, Mark W, Leonard, Mark, Clynes, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170212/ https://www.ncbi.nlm.nih.gov/pubmed/21781345 http://dx.doi.org/10.1186/1472-6750-11-78

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