Between-centre differences and treatment effects in randomized controlled trials: A case study in traumatic brain injury

BACKGROUND: In Traumatic Brain Injury (TBI), large between-centre differences in outcome exist and many clinicians believe that such differences influence estimation of the treatment effect in randomized controlled trial (RCTs). The aim of this study was to assess the influence of between-centre dif...

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Detalles Bibliográficos
Autores principales: Lingsma, Hester F, Roozenbeek, Bob, Perel, Pablo, Roberts, Ian, Maas, Andrew IR, Steyerberg, Ewout W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170218/
https://www.ncbi.nlm.nih.gov/pubmed/21867540
http://dx.doi.org/10.1186/1745-6215-12-201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170218/
https://www.ncbi.nlm.nih.gov/pubmed/21867540
http://dx.doi.org/10.1186/1745-6215-12-201

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