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Downregulation of CDKN2A and suppression of cyclin D1 gene expressions in malignant gliomas
BACKGROUND: Malignant gliomas are the most common in central nervous system cancer. Genome-wide association study identifies that CDKN2A was a susceptibility loci for glioma. The CDKN2A/cyclin-dependent kinase 4, 6/Retinoblastoma protein (Rb) pathway is thought to play a crucial role in malignant gl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170227/ https://www.ncbi.nlm.nih.gov/pubmed/21843312 http://dx.doi.org/10.1186/1756-9966-30-76 |