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Worsening of Cardiomyopathy Using Deflazacort in an Animal Model Rescued by Gene Therapy

We have previously demonstrated that gene therapy can rescue the phenotype and extend lifespan in the delta-sarcoglycan deficient cardiomyopathic hamster. In patients with similar genetic defects, steroids have been largely used to slow down disease progression. Aim of our study was to evaluate the...

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Detalles Bibliográficos
Autores principales: Rotundo, Ida Luisa, Faraso, Stefania, De Leonibus, Elvira, Nigro, Gerardo, Vitiello, Carmen, Lancioni, Alessio, Di Napoli, Daniele, Castaldo, Sigismondo, Russo, Vincenzo, Russo, Fabio, Piluso, Giulio, Auricchio, Alberto, Nigro, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170375/
https://www.ncbi.nlm.nih.gov/pubmed/21931833
http://dx.doi.org/10.1371/journal.pone.0024729