Astrocytes from Familial and Sporadic ALS Patients are Toxic to Motor Neurons

Amyotrophic Lateral Sclerosis (ALS) is a fatal motor neuron (MN) disease with astrocytes implicated as a significant contributor to MN death in familial ALS (fALS)(1–5). However, these conclusions, in part, derive from rodent models of fALS based upon dominant mutations within the superoxide dismuta...

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Detalles Bibliográficos
Autores principales: Haidet-Phillips, Amanda M., Hester, Mark E., Miranda, Carlos J., Meyer, Kathrin, Braun, Lyndsey, Frakes, Ashley, Song, SungWon, Likhite, Shibi, Murtha, Matthew J., Foust, Kevin D., Rao, Meghan, Eagle, Amy, Kammesheidt, Anja, Christensen, Ashley, Mendell, Jerry R., Burghes, Arthur H.M., Kaspar, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170425/
https://www.ncbi.nlm.nih.gov/pubmed/21832997
http://dx.doi.org/10.1038/nbt.1957

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