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CLSM as Quantitative Method to Determine the Size of Drug Crystals in a Solid Dispersion

PURPOSE: To test whether confocal laser scanning microscopy (CLSM) can be used as an analytical tool to determine the drug crystal size in a powder mixture or a crystalline solid dispersion. METHODS: Crystals of the autofluorescent drug dipyridamole were incorporated in a matrix of crystalline manni...

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Detalles Bibliográficos
Autores principales:	de Waard, Hans, Hessels, Martin J. T., Boon, Maarten, Sjollema, Klaas A., Hinrichs, Wouter L. J., Eissens, Anko C., Frijlink, Henderik W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2011
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170464/ https://www.ncbi.nlm.nih.gov/pubmed/21607777 http://dx.doi.org/10.1007/s11095-011-0484-8

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