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Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein Tax

BACKGROUND: Oncoprotein Tax, encoded by the human T-cell leukemia virus type 1 (HTLV1), persistently induces NF-κB activation, which contributes to HTLV1-mediated T-cell transformation. Recent studies suggest that the signaling function of Tax requires its ubiquitination, although how the Tax ubiqui...

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Detalles Bibliográficos
Autores principales: Wu, Xuefeng, Zhang, Minying, Sun, Shao-Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170579/
https://www.ncbi.nlm.nih.gov/pubmed/21824392
http://dx.doi.org/10.1186/2045-3701-1-27