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Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein Tax
BACKGROUND: Oncoprotein Tax, encoded by the human T-cell leukemia virus type 1 (HTLV1), persistently induces NF-κB activation, which contributes to HTLV1-mediated T-cell transformation. Recent studies suggest that the signaling function of Tax requires its ubiquitination, although how the Tax ubiqui...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170579/ https://www.ncbi.nlm.nih.gov/pubmed/21824392 http://dx.doi.org/10.1186/2045-3701-1-27 |