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Radiofrequency Ablation of Hepatocellular Carcinoma: A Literature Review

Radiofrequency ablation (RFA) of liver cancers can be performed safely using percutaneous, laparoscopic, or open surgical techniques, and much of the impetus for the use of RFA has come from cohort series that have provided an evidence base for this technique. Here, we give an overview of the curren...

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Detalles Bibliográficos
Autores principales: Minami, Yasunori, Kudo, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170722/
https://www.ncbi.nlm.nih.gov/pubmed/21994847
http://dx.doi.org/10.4061/2011/104685
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author Minami, Yasunori
Kudo, Masatoshi
author_facet Minami, Yasunori
Kudo, Masatoshi
author_sort Minami, Yasunori
collection PubMed
description Radiofrequency ablation (RFA) of liver cancers can be performed safely using percutaneous, laparoscopic, or open surgical techniques, and much of the impetus for the use of RFA has come from cohort series that have provided an evidence base for this technique. Here, we give an overview of the current status of radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC), including its physical properties, to assess the characteristics that make this technique applicable in clinical practice. We review the technical development of probe design and summarize current indications and outcomes of reported clinical use. An accurate evaluation of treatment response is very important to secure successful RFA therapy since a sufficient safety margin (at least 0.5 cm) can prevent local tumor recurrences. We also provide a profile of side effects and information on the integration of this technique into the general management of patients with HCC. To minimize complications of RFA, physicians should be familiar with each feature of complication. Appropriate management of complications is essential for successful RFA treatment. Moreover, adjuvant therapy, such as molecular targeted therapies following curative therapy, is expected to further improve survival after RFA.
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spelling pubmed-31707222011-10-12 Radiofrequency Ablation of Hepatocellular Carcinoma: A Literature Review Minami, Yasunori Kudo, Masatoshi Int J Hepatol Review Article Radiofrequency ablation (RFA) of liver cancers can be performed safely using percutaneous, laparoscopic, or open surgical techniques, and much of the impetus for the use of RFA has come from cohort series that have provided an evidence base for this technique. Here, we give an overview of the current status of radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC), including its physical properties, to assess the characteristics that make this technique applicable in clinical practice. We review the technical development of probe design and summarize current indications and outcomes of reported clinical use. An accurate evaluation of treatment response is very important to secure successful RFA therapy since a sufficient safety margin (at least 0.5 cm) can prevent local tumor recurrences. We also provide a profile of side effects and information on the integration of this technique into the general management of patients with HCC. To minimize complications of RFA, physicians should be familiar with each feature of complication. Appropriate management of complications is essential for successful RFA treatment. Moreover, adjuvant therapy, such as molecular targeted therapies following curative therapy, is expected to further improve survival after RFA. SAGE-Hindawi Access to Research 2011 2011-05-11 /pmc/articles/PMC3170722/ /pubmed/21994847 http://dx.doi.org/10.4061/2011/104685 Text en Copyright © 2011 Y. Minami and M. Kudo. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Minami, Yasunori
Kudo, Masatoshi
Radiofrequency Ablation of Hepatocellular Carcinoma: A Literature Review
title Radiofrequency Ablation of Hepatocellular Carcinoma: A Literature Review
title_full Radiofrequency Ablation of Hepatocellular Carcinoma: A Literature Review
title_fullStr Radiofrequency Ablation of Hepatocellular Carcinoma: A Literature Review
title_full_unstemmed Radiofrequency Ablation of Hepatocellular Carcinoma: A Literature Review
title_short Radiofrequency Ablation of Hepatocellular Carcinoma: A Literature Review
title_sort radiofrequency ablation of hepatocellular carcinoma: a literature review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170722/
https://www.ncbi.nlm.nih.gov/pubmed/21994847
http://dx.doi.org/10.4061/2011/104685
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