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Determination of ADAMTS13 and Its Clinical Significance for ADAMTS13 Supplementation Therapy to Improve the Survival of Patients with Decompensated Liver Cirrhosis
The liver plays a central role in hemostasis by synthesizing clotting factors, coagulation inhibitors, and fibrinolytic proteins. Liver cirrhosis (LC), therefore, impacts on both primary and secondary hemostatic mechanisms. ADAMTS13 is a metalloproteinase, produced exclusively in hepatic stellate ce...
Autores principales: | Uemura, Masahito, Fujimura, Yoshihiro, Ko, Saiho, Matsumoto, Masanori, Nakajima, Yoshiyuki, Fukui, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170842/ https://www.ncbi.nlm.nih.gov/pubmed/21994870 http://dx.doi.org/10.4061/2011/759047 |
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