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Repression of KIAA1199 attenuates Wnt-signalling and decreases the proliferation of colon cancer cells
BACKGROUND: The KIAA1199 transcript is upregulated in colon adenomas and downregulated upon β-catenin knockdown. METHODS: Transcript profiling was performed on >500 colon biopsies, methylation profiling data were compared with transcript data. Immunohistochemistry assessed KIAA1199 protein expres...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170968/ https://www.ncbi.nlm.nih.gov/pubmed/21772334 http://dx.doi.org/10.1038/bjc.2011.268 |