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Wnt–β-catenin–Tcf-4 signalling-modulated invasiveness is dependent on osteopontin expression in breast cancer

BACKGROUND: We have previously demonstrated that Tcf-4 regulates osteopontin (OPN) in rat breast epithelial cells, Rama37. In this report, we have examined the importance of this regulation in human breast cancer. METHODS: The regulatory roles of Tcf-4 on cell invasion and OPN expression were invest...

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Detalles Bibliográficos
Autores principales:	Ravindranath, A, Yuen, H-F, Chan, K-K, Grills, C, Fennell, D A, Lappin, T R, El-Tanani, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170969/ https://www.ncbi.nlm.nih.gov/pubmed/21772333 http://dx.doi.org/10.1038/bjc.2011.269

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