Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: confirmation of OCT3/4 specificity for germ cell tumours

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BACKGROUND: OCT3/4 (POU5F1) is an established diagnostic immunohistochemical marker for specific histological variants of human malignant germ cell tumours (GCTs), including the seminomatous types and the stem cell component of non-seminomas, known as embryonal carcinoma. OCT3/4 is crucial for the r...

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Detalles Bibliográficos
Autores principales: Rijlaarsdam, M A, van Herk, H A D M, Gillis, A J M, Stoop, H, Jenster, G, Martens, J, van Leenders, G J L H, Dinjens, W, Hoogland, A M, Timmermans, M, Looijenga, L H J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171004/
https://www.ncbi.nlm.nih.gov/pubmed/21847120
http://dx.doi.org/10.1038/bjc.2011.270
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