Mechanism for modulation of gating of connexin26-containing channels by taurine

The mechanisms of action of endogenous modulatory ligands of connexin channels are largely unknown. Previous work showed that protonated aminosulfonates (AS), notably taurine, directly and reversibly inhibit homomeric and heteromeric channels that contain Cx26, a widely distributed connexin, but not...

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Detalles Bibliográficos
Autores principales: Locke, Darren, Kieken, Fabien, Tao, Liang, Sorgen, Paul L., Harris, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171079/
https://www.ncbi.nlm.nih.gov/pubmed/21844220
http://dx.doi.org/10.1085/jgp.201110634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171079/
https://www.ncbi.nlm.nih.gov/pubmed/21844220
http://dx.doi.org/10.1085/jgp.201110634

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