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Anti–IL-20 monoclonal antibody inhibits the differentiation of osteoclasts and protects against osteoporotic bone loss
IL-20 is a proinflammatory cytokine of the IL-10 family that is involved in psoriasis, rheumatoid arthritis, atherosclerosis, and stroke. However, little is known about the role of IL-20 in bone destruction. We explored the function of IL-20 in osteoclastogenesis and the therapeutic potential of ant...
Autores principales: | Hsu, Yu-Hsiang, Chen, Wei-Yu, Chan, Chien-Hui, Wu, Chih-Hsing, Sun, Zih-Jie, Chang, Ming-Shi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171097/ https://www.ncbi.nlm.nih.gov/pubmed/21844205 http://dx.doi.org/10.1084/jem.20102234 |
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