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A retinoic acid–dependent checkpoint in the development of CD4(+) T cell–mediated immunity
It is known that vitamin A and its metabolite, retinoic acid (RA), are essential for host defense. However, the mechanisms for how RA controls inflammation are incompletely understood. The findings presented in this study show that RA signaling occurs concurrent with the development of inflammation....
Autores principales: | Pino-Lagos, Karina, Guo, Yanxia, Brown, Chrysothemis, Alexander, Matthew P., Elgueta, Raúl, Bennett, Kathryn A., De Vries, Victor, Nowak, Elizabeth, Blomhoff, Rune, Sockanathan, Shanthini, Chandraratna, Roshantha A., Dmitrovsky, Ethan, Noelle, Randolph J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171100/ https://www.ncbi.nlm.nih.gov/pubmed/21859847 http://dx.doi.org/10.1084/jem.20102358 |
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