Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

Receptor-like tyrosine kinase (RYK) functions as a transmembrane receptor for the Wnt family of secreted protein ligands. Although RYK undergoes endocytosis in response to Wnt, the mechanisms that regulate its internalization and concomitant activation of Wnt signaling are unknown. We discovered tha...

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Detalles Bibliográficos
Autores principales: Berndt, Jason D., Aoyagi, Atsushi, Yang, Peitzu, Anastas, Jamie N., Tang, Lan, Moon, Randall T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171123/
https://www.ncbi.nlm.nih.gov/pubmed/21875946
http://dx.doi.org/10.1083/jcb.201107021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171123/
https://www.ncbi.nlm.nih.gov/pubmed/21875946
http://dx.doi.org/10.1083/jcb.201107021

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