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Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype
Although a large number of actin-binding proteins and their regulators have been identified through classical approaches, gaps in our knowledge remain. Here, we used genome-wide RNA interference as a systematic method to define metazoan actin regulators based on visual phenotype. Using comparative s...
Autores principales: | Rohn, Jennifer L., Sims, David, Liu, Tao, Fedorova, Marina, Schöck, Frieder, Dopie, Joseph, Vartiainen, Maria K., Kiger, Amy A., Perrimon, Norbert, Baum, Buzz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171124/ https://www.ncbi.nlm.nih.gov/pubmed/21893601 http://dx.doi.org/10.1083/jcb.201103168 |
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