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The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins
Neuropilin 1 (NRP1) is a transmembrane glycoprotein that is essential for blood vessel development in vertebrates. Best known for its ability to bind members of the vascular endothelial growth factor (VEGF) and class 3 semaphorin families through its extracellular domain, it also has a highly conser...
Autores principales: | Fantin, Alessandro, Schwarz, Quenten, Davidson, Kathryn, Normando, Eduardo M., Denti, Laura, Ruhrberg, Christiana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Company of Biologists
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171219/ https://www.ncbi.nlm.nih.gov/pubmed/21852397 http://dx.doi.org/10.1242/dev.070037 |
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