Ex Vivo Expansion of Human Hematopoietic Stem Cells by Garcinol, a Potent Inhibitor of Histone Acetyltransferase

BACKGROUND: Human cord blood (hCB) is the main source of hematopoietic stem and progenitor cells (HSCs/PCs) for transplantation. Efforts to overcome relative shortages of HSCs/PCs have led to technologies to expand HSCs/PCs ex vivo. However, methods suitable for clinical practice have yet to be full...

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Detalles Bibliográficos
Autores principales: Nishino, Taito, Wang, Changshan, Mochizuki-Kashio, Makiko, Osawa, Mitsujiro, Nakauchi, Hiromitsu, Iwama, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171405/
https://www.ncbi.nlm.nih.gov/pubmed/21931675
http://dx.doi.org/10.1371/journal.pone.0024298

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